Syncra vs Deep 6 AI
Two approaches to clinical trial enrollment risk — one runs on EHR pulls, the other runs on the protocol itself.
Sponsor Ops teams evaluating clinical trial enrollment software usually land on the same shortlist: Deep 6 AI for AI-driven patient-trial matching, and Syncra for pre-pilot risk scoring plus network-wide coordination. Both products sit in the 'AI for clinical trials' category — they solve different parts of the problem and they reach the answer at different points in your timeline.
Deep 6 AI excels at per-patient matching inside institutions where you already have a data use agreement. Syncra's Instant Risk Report scores enrollment risk before you've onboarded a single site, using public protocol metadata and sponsor-supplied PDFs. If your bottleneck is 'which trial is going to miss enrollment,' Syncra answers in 30 seconds. If your bottleneck is 'find me the next eligible patient at this one site,' Deep 6 AI's EHR-pull flow is built for that.
This page walks through both products across five dimensions sponsor Ops cares about most: data sources, scoring methodology, daily outputs, multi-site behavior, and pricing posture.
| Dimension | Syncra | Deep 6 AI |
|---|---|---|
| Data sources | ClinicalTrials.gov v2 protocol metadata plus sponsor-supplied protocol PDFs summarized by an OpenAI extractor. Instant — no site agreements, no EHR ingest to start. [1] | Deidentified institutional EHR records (labs, ICD-10 codes, clinical notes). Per-site data use agreements required before any scoring runs. [2] |
| Scoring methodology | 0–100 portfolio/trial-level Enrollment Risk Score tuned against Tufts CSDD benchmarks (indication feasibility, phase, site count, target N, window, criteria complexity). Per-patient scoring available after EHR integration. [3] | Probabilistic per-patient match score per candidate — oriented to 'is THIS patient a fit for THIS trial' rather than 'will THIS trial miss enrollment.' [2] |
| Outputs | 1-page PDF enrollment risk report emailed within ~30 seconds, daily recruiter queue of next-best patients, Multi-Site Coordinator daily plan. [1] | Ranked list of candidate patients per site/cohort, surfaced into the site's existing workflow through an EHR-integrated app. [2] |
| Multi-site support | Built-in cross-site capacity rebalancing and conflict avoidance — the Multi-Site Coordinator allocates each new referral to the open cohort slot across the network. [1] | Site-scoped rankings — each site gets its own independent candidate list. Cross-network coordination is the sponsor's job. [2] |
| Pricing posture | Pilot-led. Instant Risk Report funnel is free. Paid engagement only after a pilot closes. [1] | Enterprise SaaS contract, quote-based, typically six-figure annual fees. [2] |
The two products are complementary more than competitive — but sponsor Ops rarely has the bandwidth to evaluate two vendors in parallel. If you don't yet have a per-site enrollment fire (i.e., you're still choosing which trials to greenlight), Syncra's pre-pilot risk score is the cheaper signal: it runs before any EHR agreement and tells you which trial deserves the budget for a Deep 6 AI–style site integration in the first place.
If you already run multiple competing trials across a site network, the Multi-Site Coordinator fills a capability Deep 6 AI doesn't claim: cross-site capacity rebalancing and conflict avoidance between trials competing for the same patient pool. Combined with Syncra's per-trial risk score, that gives your Ops team a clean handoff between portfolio triage (Syncra) and per-site patient finding (Deep 6 AI).
Drop in an NCT number and a work email. We pull the protocol, score it, and email you a 1-page risk report within ~30 seconds. No EHR integration needed.
Run Instant Risk Report on your trial →